SCEP Exclusions lists limit

Question

Hi all is there a limit to System Center Endpoint Protection with SCCM 2012 R2 exclusions for files, extensions and paths?
I'm looking into creating a global server policy and a global workstation policy which will be aimed to be deployed to 5000 workstations and 600 servers.  I'd like to have the policies as minimal as possible so to avoid having to create multiple collections
to target to.
Based on based on our current Symantec environment we have over 150 file extension exclusions 100 folder paths and  and under 50 processes that we want to add to exclusions.
Would it be wise to have limited policies?  Is there any performance impact if there are soo many exclusions listed under 1 policy?

Answer 1

It depends on how you setup these policies. One good practice could be setup exclusion base on target users. For example you might have several exclusions for PCs targeted to trusted developers while you won't exclude anything when it is target public PC
or security-critical systems.
Before deploy them try run a small testing environment and try apply your policies and monitor their impacts on the system (e.g. performance, scan duration, etc.)