Scrubbing Audio causes AE to beachball

Question

Computer (OSX 10.6.8)
Mac Pro 4.1
Model Identifier: MacPro4,1
  Processor Name: Quad-Core Intel Xeon
  Processor Speed: 2.93 GHz
  Number Of Processors: 2
  Total Number Of Cores: 8
  L2 Cache (per core): 256 KB
  L3 Cache (per processor): 8 MB
  Memory: 16 GB
After Effect Settings (CS5 v 10.0.2)
Preview - Open GL is off  (behavior is the same with Open GL on)
               Audio Duration set to 30 seconds
Disc Cache - 2GB
Memory - Installed Ram: 16GB
               Ram reserved for other programs: 6GB
Render Multiple Frames (usually set to off, but behavior is same with it on)
       Cores: 16
       CPU reserved: 3
       RAM/CPU: 3GB
As the title says, scrubbing any audio inside of After Effects causes the program to beachball, pegging processor use at 100.9% and the program gets marked as not responding. By scrubbing audio, I mean holding down the command key while dragging through the timeline to preview the video with the audio for timing cuts and hits. This is happening with projects that only contain an image sequence and a sound file, projects with 3d camera moves and multiple layers... pretty much if I have  to bring a sound file in to AE, I know it will crash when I need to check the audio.
I have tried opening a fresh project with only an audio file (a new project for each a wav, a mp3, and an m4a) and attempting to scrub through the timeline causes AE to freeze.
I am beyond frustrated at this point, as quick projects have turned in to days of work. Any ideas on how to revert AE back to a usable product are greatly appreciated.

Answer 1

Sorry for the delay in response, I was on vacation and have just gotten caught up enough to return to this issue.
I had the most recent Wacom drivers when reporting the issue. There was a new version released today and I have updated to that. Updating the wacom driver did not resolve the issue.
OpenGL is disabled. The issue persists with OpenGL enabled.
I disabled "hardware accelerate panels" and I am able to now scrub through a single audio track of any format on the second try.
I attempt to scrub through a track and my machine beach balls for a minute
I regain control of the program and am able to scrub through a single audio file
When I get to a second audio file in the timeline my machine beachballs and After Effects stops responding just like before
Here is the most recent crash log - http://pastebin.com/cxBujE9F 
This happens when switching from a wav to a wav, form a wav to an aif, wav to mp3, mp3 to wav, etc. It will freeze for a moment on the first file and completely hang on the second file.
As for audio preferences
Audio Hardware:
Default Device: System Default
Buffer Size: 512
Audio Output Mapping:
Map output for: System Default
Left: Headphones 1
Right: Headphones 2
Output:
Audio Block Duration: 0:00:01:00