Setup Matrix volume Doubts

Hi experts,
I have a couple of questions concerning the setup matrix volume.
1-a)What setup matrix combination volume is considered  as acceptable?
   b)Which is the break point from where performance issues take place?
3-What happens if the optimizer is optimizing orders and within those orders , there are features which are not included in the matrix.If this eventuality occurs, how the optimizer reacts?
Regards,
Analí

Thanks a lot for your advise Frank!!
Question Still pending review:
3-What happens if the optimizer is optimizing orders and within those orders , there are features which are not included in the matrix.If this eventuality occurs, how the optimizer reacts?
regards,
Analí

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    replace the existing rules with one that does not specify the port [L3 rule].
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