Since i downloaded update it wont work?

I have a new macbook, 10.5.1 and have used garageband a few times already. I downloaded the rest of the instruments and apple loops as part as the update. At the end it said something could not be installed.
After my computer restarted, it installed the updates and when i tried to open garageband it wont open anymore. It came up with an error saying "this file is not supported. abort" four times and then another error saying "8 invalid region(s) changed!"
Now my garageband wont open all, after downloading the update..
I am new to the mac operating system having switched from windows... any ideas how to fix this?
Message was edited by: drury87

Did you download the instruments and loops from the DVD?
Go to Library>Preferences and find, com.apple.garageband.cs and com.apple.garageband.plist put them in the trash. See if garageband opens. If it does and you need to install the loops/instruments do it from the dvd.

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