Skype Causing USB Headset to Code 45

For whatever reason, the prolonged use of Skype for a voice call will cause my headset in the device manager to code 45, or disconnect from my computer without actually being disconnected. Pressing CAPS/NUM/SCROLL lock, or running dxdiag causes the same error to occur. I've tried reinstalling the USB driver, the keyboard driver (Razer Blackwidow Ultimate), and rolling back Skype with no success.
I've also noticed that there are corresponding "Audit Success" entries in the Event Viewer under Security, many of them labeled as either "Account successfully logged off" or logged on with either very close times, or the exact same times. 
I've even disabled the NVIDIA audio drivers. There are also no new drivers for my sound card. 

There's always the possibility of faulty/failing onboard USB or USB ports/onboard power issue.  You could also try a powered USB hub connected to one of the ports to see if anything changes.  The big oddity is it failing with dxdiag and using the keyboard keys.  You have the option to try other versions of Skype to see if anything in Skype is causing it or even do a Skype settings/profile reset.  Other than that you may have some odd USB hardware, software conflict or an onboard overheating issue.  You might want to test out the scenario in Safe Mode with networking, disable background apps (possibly touchpad/keyboard software), remove other USB hardware connected.  There's always a possibility you updated some software or driver and it's causing a conflict.  I'd hope there wouldn't be a conflicting issue with the onboard keyboard.
If you haven't done it in the past you might want to remove the USB root hub that this device is connected to in device manager.  If you remove the correct one that represents the onobard the it's connected to, the device will effectively totally uninstall an re-install like the first time.  This style of purge may resolve this oddity as well. 

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