Slow mail = beach ball spins with every click in every field.

This happens since installing Snow Leopard: every click in mail takes 5 or 10 seconds for anything to happen. Reaction was always instant before. Anyone know of any fix?
Examples of when this happens:
When I click on "Forward."
When I click "New Message" to pull up the blank email form.
When I click on the "To" line.
When I click on any other field to compose and send an email.
That is, when I click on anything.
Thank you for any advice.

Some other post (which one?) contained the resolution: Go under the "Mailbox" menu and select "Rebuild" for each account. Count on it taking a while.

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      Total number of backups: 9
      Oldest backup: 2014-04-01 22:47:45 +0000
      Last backup: 2014-10-01 17:35:40 +0000
      Size of backup disk: Excellent
      Backup size 500.10 GB > (Disk size 0 B X 3)
    Top Processes by CPU: ℹ️
          21% Mail
          7% syslogd
          4% WindowServer
          0% AppleSpell
          0% sysmond
    Top Processes by Memory: ℹ️
      503 MB Mail
      86 MB InterCheck
      64 MB Finder
      64 MB SophosScanD
      56 MB Safari
    Virtual Memory Information: ℹ️
      87 MB Free RAM
      1.22 GB Active RAM
      1.34 GB Inactive RAM
      1.02 GB Wired RAM
      1.48 GB Page-ins
      23 MB Page-outs
    Diagnostics Information: ℹ️
      Jan 24, 2015, 06:17:55 PM Self test - passed

    Remove Sophos. This antivirus application is unnecessary.
    http://www.sophos.com/en-us/support/knowledgebase/120838.aspx

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