Slow running after 10.10.1 installed

My 2011 macbook pro is running frustratingly slow after downloading 10.10.1 system. From start up to opening applications and trying to use them. Any solutions?

Problem description:
all systems are running slow since downloading 10.10.1
EtreCheck version: 2.1.6 (109)
Report generated 23 January 2015 8:56:33 am NZDT
Download EtreCheck from http://etresoft.com/etrecheck
Click the [Support] links for help with non-Apple products.
Click the [Details] links for more information about that line.
Click the [Adware] links for help removing adware.
Hardware Information: ℹ️
MacBook Pro (15-inch, Early 2011) (Technical Specifications)
MacBook Pro - model: MacBookPro8,2
1 2 GHz Intel Core i7 CPU: 4-core
4 GB RAM Upgradeable
BANK 0/DIMM0
2 GB DDR3 1333 MHz ok
BANK 1/DIMM0
2 GB DDR3 1333 MHz ok
Bluetooth: Old - Handoff/Airdrop2 not supported
Wireless: en1: 802.11 a/b/g/n
Battery Health: Normal - Cycle count 388
Video Information: ℹ️
Intel HD Graphics 3000 - VRAM: 384 MB
Color LCD 1440 x 900
AMD Radeon HD 6490M - VRAM: 256 MB
System Software: ℹ️
OS X 10.10.1 (14B25) - Time since boot: 1:28:8
Disk Information: ℹ️
TOSHIBA MK5065GSXF disk0 : (500.11 GB)
EFI (disk0s1) <not mounted> : 210 MB
Recovery HD (disk0s3) <not mounted> [Recovery]: 650 MB
Macintosh HD (disk1) / : 498.88 GB (175.11 GB free)
Core Storage: disk0s2 499.25 GB Online
MATSHITADVD-R   UJ-898
USB Information: ℹ️
Apple Inc. FaceTime HD Camera (Built-in)
Apple Inc. Apple Internal Keyboard / Trackpad
Apple Inc. BRCM2070 Hub
Apple Inc. Bluetooth USB Host Controller
Apple Computer, Inc. IR Receiver
Thunderbolt Information: ℹ️
Apple Inc. thunderbolt_bus
Gatekeeper: ℹ️
Anywhere
Kernel Extensions: ℹ️
/Library/Application Support/Kaspersky Lab/KAV/Bases/Cache
[loaded] com.kaspersky.kext.kimul.44 (44) [Support]
[loaded] com.kaspersky.kext.mark.1.0.5 (1.0.5) [Support]
/System/Library/Extensions
[loaded] com.kaspersky.kext.klif (3.0.5d45) [Support]
[loaded] com.kaspersky.nke (2.0.0d12) [Support]
Launch Agents: ℹ️
[running] com.brother.LOGINserver.plist [Support]
[loaded] com.google.keystone.agent.plist [Support]
[running] com.kaspersky.kav.gui.plist [Support]
[loaded] com.maintain.CocktailSystemEvents.plist [Support]
Launch Daemons: ℹ️
[failed] com.adobe.fpsaud.plist [Support]
[loaded] com.google.keystone.daemon.plist [Support]
[running] com.kaspersky.kav.plist [Support]
[not loaded] com.maintain.CocktailScheduler.plist [Support]
[loaded] com.skype.skypeinstaller.plist [Support]
User Launch Agents: ℹ️
[loaded] com.adobe.ARM.[...].plist [Support]
[invalid?] com.zeobit.MacKeeper.Helper [Support]
User Login Items: ℹ️
SpeechSynthesisServer Application (/System/Library/Frameworks/ApplicationServices.framework/Versions/A/Frameworks /SpeechSynthesis.framework/Versions/A/SpeechSynthesisServer.app)
Dropbox Application (/Applications/Dropbox.app)
AdobeResourceSynchronizer Application Hidden (/Applications/Adobe Reader.app/Contents/Support/AdobeResourceSynchronizer.app)
Internet Plug-ins: ℹ️
FlashPlayer-10.6: Version: 16.0.0.287 - SDK 10.6 [Support]
Default Browser: Version: 600 - SDK 10.10
AdobePDFViewerNPAPI: Version: 11.0.10 - SDK 10.6 [Support]
AdobePDFViewer: Version: 11.0.10 - SDK 10.6 [Support]
Flash Player: Version: 16.0.0.287 - SDK 10.6 [Support]
QuickTime Plugin: Version: 7.7.3
Google Earth Web Plug-in: Version: 6.0 [Support]
Silverlight: Version: 3.0.40818.0 [Support]
iPhotoPhotocast: Version: 7.0 - SDK 10.8
Safari Extensions: ℹ️
vkbd [Cached]
URLAdvisor [Cached]
Virtual Keyboard [Installed]
URL Advisor [Installed]
3rd Party Preference Panes: ℹ️
Flash Player [Support]
Time Machine: ℹ️
Skip System Files: NO
Mobile backups: OFF
Auto backup: NO - Auto backup turned off
Volumes being backed up:
Macintosh HD: Disk size: 498.88 GB Disk used: 323.76 GB
Destinations:
Seagate Backup Plus Drive [Local]
Total size: 999.86 GB
Total number of backups: 2
Oldest backup: 2014-09-17 06:52:16 +0000
Last backup: 2014-10-05 22:22:33 +0000
Size of backup disk: Adequate
Backup size 999.86 GB > (Disk used 323.76 GB X 3)
Top Processes by CPU: ℹ️
      6% WindowServer
      0% kav
      0% fontd
      0% kav_agent
      0% AppleSpell
Top Processes by Memory: ℹ️
210 MB kav
176 MB Safari
142 MB softwareupdated
133 MB com.apple.WebKit.WebContent
133 MB Pages
Virtual Memory Information: ℹ️
191 MB Free RAM
1.39 GB Active RAM
1.63 GB Inactive RAM
1.04 GB Wired RAM
2.68 GB Page-ins
57 MB Page-outs
Diagnostics Information: ℹ️
Jan 23, 2015, 07:29:14 AM Self test - passed
Standard users cannot read /Library/Logs/DiagnosticReports.
Run as an administrator account to see more information.

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Slow running after 10.10.1 installed

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