Software update killed Eudora - I cannot send mail now.  ???????

OS X 10.4.11
Software update told me that I should download and install a new security update, and being the compliant soul that I am, I complied. Big mistake. Mac.com will not allow me to send email from Eudora. I have changed nothing. The SMTP Server in Eudora prefs is still smtp.mac.com. I can still get my mail.
Any ideas?
Thanks, Steve

Thanks for the information. I did the permissions repair with no improvement, but have not gone beyond that because...
My virus checker found and removed the following:
file name detected as
.BC.Mob1Au W32/Bagle.dldr
.BC.K4jZVA W32/Bagle.dldr.gen
.BC.jyyxdn W32/Bagle.dldr
.BC.Eh5oyy W32/Bagle.dldr
.BC.d2rdKk W32/Bagle.dldr.gen
.BC.uUYciN W32/Bagle.gen
In addition, my wife checked her yahoo mail account and found the following message. This is wierd because she did not send any mail through yahoo.
Note: Forwarded message is attached.
Hi. This is the qmail-send program at 30-245.bluehost.com.
I'm afraid I wasn't able to deliver your message to the following addresses.
This is a permanent error; I've given up. Sorry it didn't work out.
<edited by host>
Connected to 209.85.222.35 but greeting failed.
Remote host said: 421-4.7.0 [74.220.200.204] Our system has detected an unusual amount of
421-4.7.0 unsolicited mail originating from your IP address. To protect our
421-4.7.0 users from spam, mail sent from your IP address has been temporarily
421-4.7.0 blocked. Please visit http://www.google.com/mail/help/bulk_mail.html
421 4.7.0 to review our Bulk Email Senders Guidelines. 1si7626834pzk.72
I'm not going to try again; this message has been in the queue too long.
--- Enclosed are the original headers of the message.
-----Inline Message Follows-----
(Body supressed)
Could this mean that a virus has turned our machine into a spam generator? If so, perhaps mac.com has blocked us.

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