Some Applications Just Stopped Working

I can't seem to get ITunes, Safari, GoogleEarth, Skype, and a few others to work, while others work fine Firefox, IPhoto, MSOffice, Garageband, Appleworks, etc. The last time I used this was with ITunes and I usually just put the computer to sleep each night. Up until now, no problems, now key applications just don't work. They bounce once in the doc and then nothing. I have tries restarting but no change. Please advise.

Hello again:
"Changed software" means that you added or subtracted software prior to the problems. You most assuredly have, by the by, based on your answer.
IM not so humble opinion, the Safari 3 Beta (as miriam suggested earlier) is at the root of your problems. Why Apple released beta software to the general public is beyond me (beta=bugs).
I hope you are able to find your copy of OS X 10.4 as I am relatively confident you have directory problems. Repairing directory problems may be done by either using the disk utility from the software install DVD or by purchasing a third party program. DiskWarrior is very good, but it costs about $90. If you find your software install DVD, I would opt for an archive and install of OS X 10.4.
Barry

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