Some users can't open PDFs

Hello
We have an issue with some users not being able to open or save PDFs.
This is only happing with a few users.
It happens through the browser AND through SharePoint views in our CRM (Dynamics), so not a browser issue.
They can open the document by using the contextual menu on the document.
They can't open it by clicking directly on the document link.
Any ideas much appreciated!
*UPDATE*
One user also can't open emails that have been uploaded.

First thing would be to update and repair Adobe Reader on the users affected.
Check which version of Reader they've got and compare it to yours/others whom got it working.
Disable addons/plugins (even if they're sharepoint related)

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Some users can't open PDFs

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