Spinning ball pops up every time and the top menu bar keeps flashing

The problem started today, for no apparent reason. I was working with some programs open (not many) when my screen froze. Nothing worked, so I closed the laptop to see if it would return to the home page (where you type the password) soon after I heard the 'apple sound'. The computer was restarted, when opened, there was a gray folder with an white question mark flashing in the center of the screen. I restarted the computer again.
From this time he began to have symptoms that persist until now:
• Every time I do some action on any application the spinning beach ball appears and for a few seconds the program is locked.
• The top menu bar - where the icons are located ( bluetooth, dropbox, battery, spotlight, etc.) flashes every 40 seconds.
I use this computer for work and thus can hardly surf the internet.
I hope someone can help me finding a solution to this.
Below are the data collected through the EtreCheck app about my computer:
Hardware Information:
  MacBook Pro (15-inch, Mid 2012) (Verified)
  MacBook Pro - model: MacBookPro9,1
  1 2.3 GHz Intel Core i7 CPU: 4 cores
  8 GB RAM
Video Information:
  Intel HD Graphics 4000 - VRAM: (null)
  Color LCD 1440 x 900
  NVIDIA GeForce GT 650M - VRAM: 512 MB
System Software:
  OS X 10.9.3 (13D65) - Uptime: 0 days 1:9:27
Disk Information:
  APPLE HDD ST500LM012 disk0 : (500,11 GB)
  EFI (disk0s1) <not mounted>: 209,7 MB
  Macintosh HD (disk0s2) / [Startup]: 499,25 GB (323,02 GB free)
  Recovery HD (disk0s3) <not mounted>: 650 MB
  MATSHITADVD-R   UJ-8A8 
USB Information:
  Apple Computer, Inc. IR Receiver
  Apple Inc. Apple Internal Keyboard / Trackpad
  Apple Inc. BRCM20702 Hub
  Apple Inc. Bluetooth USB Host Controller
  Apple Inc. FaceTime HD Camera (Built-in)
  Logitech USB Optical Mouse
Thunderbolt Information:
  Apple Inc. thunderbolt_bus
Gatekeeper:
  Mac App Store and identified developers
Launch Daemons:
  [loaded] com.adobe.fpsaud.plist Support
  [not loaded] com.adobe.SwitchBoard.plist Support
  [loaded] com.microsoft.office.licensing.helper.plist Support
  [loaded] com.oracle.java.Helper-Tool.plist Support
Launch Agents:
  [not loaded] com.adobe.AAM.Updater-1.0.plist Support
  [loaded] com.adobe.CS5ServiceManager.plist Support
  [running] com.brother.LOGINserver.plist Support
  [loaded] com.oracle.java.Java-Updater.plist Support
User Launch Agents:
  [loaded] com.adobe.AAM.Updater-1.0.plist Support
User Login Items:
  iTunesHelper
  Google Drive
  Dropbox
Internet Plug-ins:
  FlashPlayer-10.6: Version: 13.0.0.214 - SDK 10.6 Support
  QuickTime Plugin: Version: 7.7.3
  Flash Player: Version: 13.0.0.214 - SDK 10.6 Outdated! Update
  AdobePDFViewer: Version: 10.1.1 Support
  Default Browser: Version: 537 - SDK 10.9
  SharePointBrowserPlugin: Version: 14.4.2 - SDK 10.6 Support
  JavaAppletPlugin: Version: Java 7 Update 45 Check version
Safari Extensions:
  YouTube Center: Version: 2.0.1
Audio Plug-ins:
  BluetoothAudioPlugIn: Version: 1.0 - SDK 10.9
  AirPlay: Version: 2.0 - SDK 10.9
  AppleAVBAudio: Version: 203.2 - SDK 10.9
  iSightAudio: Version: 7.7.3 - SDK 10.9
iTunes Plug-ins:
  Quartz Composer Visualizer: Version: 1.4 - SDK 10.9
User Internet Plug-ins:
  npsf_uni: Version: sf 3.3.2.1 Support
3rd Party Preference Panes:
  Flash Player  Support
  Java  Support
Time Machine:
  Auto backup: YES
  Volumes being backed up:
  Macintosh HD: Disk size: 464.96 GB Disk used: 164.13 GB
  Destinations:
  Data [Network] (Last used)
  Total size: 2 
  Total number of backups: 28
  Oldest backup: 2014-01-05 23:47:54 +0000
  Last backup: 2014-06-16 00:52:40 +0000
  Size of backup disk: Excellent
  Backup size 2  > (Disk size 464.96 GB X 3)
  Time Machine details may not be accurate.
  All volumes being backed up may not be listed.
Top Processes by CPU:
      8% mdworker
      3% SystemUIServer
      0% lowBatteryWarning
      0% WindowServer
      0% Dropbox
Top Processes by Memory:
  238 MB Safari
  156 MB com.apple.IconServicesAgent
  147 MB mds_stores
  131 MB systemstats
  126 MB com.apple.WebKit.WebContent
Virtual Memory Information:
  2.89 GB Free RAM
  3.15 GB Active RAM
  1.05 GB Inactive RAM
  929 MB Wired RAM
  377 MB Page-ins
  0 B Page-outs

Additional informations:
• I ran a disk repair and the message that came up was that the Macintosh HD volume seems to have no problems. But the problem still there.
• This is the results for the test that Linc suggested in other articles:
Jun 20 10:05:23 MacBook-Pro-de-Gustavo kernel[0] <Debug>: disk0s2: I/O error.
--- last message repeated 62 times ---
Jun 20 10:55:54 MacBook-Pro-de-Gustavo kernel[0] <Debug>: nspace-handler-set-snapshot-time: 1403272556
Jun 20 10:56:49 MacBook-Pro-de-Gustavo kernel[0] <Debug>: disk0s2: I/O error.
--- last message repeated 29 times ---
Jun 20 11:36:51 MacBook-Pro-de-Gustavo kernel[0] <Debug>: nspace-handler-set-snapshot-time: 1403275013
Jun 20 11:37:18 MacBook-Pro-de-Gustavo kernel[0] <Debug>: nspace-handler-unblock: did not find token 638
Jun 20 11:37:18 MacBook-Pro-de-Gustavo kernel[0] <Debug>: nspace-handler-unblock: did not find token 637
Jun 20 11:38:12 MacBook-Pro-de-Gustavo kernel[0] <Debug>: disk0s2: I/O error.
--- last message repeated 21 times ---

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