Suddenly Unable to Run Adobe Photoshop

Adobe Photoshop, both CS2 and CS, crash during launch (splash screen says 'building TWAIN menus...') with the following on the crash report:
Exception: EXCBADACCESS (0x0001)
Codes: KERNPROTECTIONFAILURE (0x0002) at 0x00000000
I have run both applications before, but not for a few months, probably before installing 10.4.9 and 10.4.10.
This happens under safe boot, and when using a newly created test account, after repairing permissions and verifying the hard drive disk.
I have sent the report to Adobe, but it is too early to expect an answer. I have checked with Applecare and been told that i did all the steps I could to isolate the problem.
Does anyone have a theory about what is going on, or what i could do besides waiting for help from Adobe? Could it have anything to do with my having Adobe Lightroom 1.1 also installed? It runs fine.

I don't know why there is a problem either--my own TWAIN driver is in place and I haven't had a problem. However, I don't have a scanner connected, so have never installed any scanner software. If you do have a scanner with its own software I suppose there could be a conflict. At any rate, I have seen other people whose PS crashes were solved by removing the Adobe TWAIN driver.
Francine
Francine
Schwieder

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I have found a solution to this problem. Install the files in safe boot mode. Here is the how to guide:
Part One:
With past attempts or even previous versions of Adobe CS can be still lying around on your mac, in order to remove the bits and bobs needed in order for a clean install you need to download the 'CS5 Cleaner Tool' by Adobe. This can remove all previous version of CS right back to CS3. This could be the problem effecting you download. This tool can be download from here: http://kb2.adobe.com/cps/829/cpsid_82947.html
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Part Two:
To start up into Safe Mode (to Safe Boot), do this:
Be sure your Mac is shut down.
Press the power button.
Immediately after you hear the startup tone, hold the Shift key. The Shift key should be held as soon as possible after the startup tone, but not before the tone.
Release the Shift key when you see the gray Apple icon and the progress indicator (looks like a spinning gear).
(Source: Apple: http://support.apple.com/kb/ht1455)
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Now that you have let your machine boot up in Safe Boot.
    1. Locate the .dmg installation file. This can take a while to load, but be patient.
    2. Click to open the .dmg.
    3. Carry on with the installation as you normally would.
    4. Sit back and enjoy until its 100%.
Once it has installed you can now restart your machine and boot up as normal. Log in and then it should be there in your applications to use.
I have spent nearly 2 days myself trying to figure this out, and finally i have found a solution. I hope this helps anyone who has come across this problem themselves.
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