System Reinstalled-now iTunes won't open

I downloaded the new iTunes yesterday and today had some computer problems and had to go reinstall my system from Monday. Now, iTunes won't open at all, I just keep getting the error "The iTunes application could not be opened. An unknown error occured." Any ideas of what I can do to fix this?

It did for me.  And I wanted to thank the group for the advice!
I was sweating bullets when it was installing.  Almost four thousand handpicked songs accumulated over four years.  Names, Dates, Album Art, etc.
I just joined to say thanks for the help/guidance!!
Shane D
PS: I was terrified to hit the delete button.

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