System settings do not react

A few weeks ago, i wanted to change my background via system settings. Suddenly the systems settings stopped and i wasnt able to close it or to come back to the main menu of the system settings. all i could do was to close it via cmd+alt+esc.
Now i got the problem, that everytime i want to open the system settings i am directed to the "background" but i cant go back to main menu because the program does not react.
Can someone help me please????

If the re-boot suggested by Shootist007 doesn't work then ensure that System Preferences is closed.  If I were you I'd go into Activity Monitor and check that the process isn't running even though you can't see the window.  Next, drag the following file to the trash:
<home>/Library/Caches/com.apple.preferencepanes.cache
Do not delete it from the trash just yet, just in case you need to restore it.  Now restart System Preferences, it will re-create the cache file and hopefully sort your problem.

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