Tascam US-122L won't work on my new iMac

Just bought a brand new iMac 3.06 GHz Intel Core 2 Duo with OSX10.6.2 and my Tascam US-122L audio interface won't work. It worked on my old PC (slowly!), and it works on my friend's iMac with OSX 10.5.8, but not on mine!
The Tascam control panel says "Device: none found", and the Garageband Audio input and output don't recognize the US-122L as being connected (they do on my friend's iMac with 10.5.8)
I've emailed Tascam - they're very quick to respond, but the suggestions of new drivers, uninstall and reinstall drivers, firmware etc have not made any difference.
Then I tried calling them - they told me it had nothing to do with 32 bit versus 64 bit, but that the new iMacs did not have enough power output from the USB ports to run the US-122L, and that I needed a powered USB hub. I've borrowed one to try, and guess what - still doesn't work!
Any suggestions would be welcome, since Tascam don't seem to be able to help.
Thanks.

I doubt that insufficient USB power is the problem (whether supplied from a powered hub or an iMac). The Tascam US-122L is a discontinued model, replaced by the "Mk II" version, but either should comply with the USB bus powered spec to draw less than 500 ma (2.5 watts) or it wouldn't work with any standard USB host & most (including iMacs) would display a warning about it drawing too much power.
I suspect this particular unit is somehow defective, in part because of the above & in part because of the "slowly" comment in the original post.

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