The application MAIL cancels my shut Dow on my Mac book pro

help please!
I am trying to power off my MacBook Pro but it tells me mail canceled the shut down.....if I click on MAIL ay top of the screen the quit mail option is grayed out, and it won't open the mail if  I click on the mail icon In the dock
what should I do??
thanks in advance,
cori

Press the COMMAND-OPTION-ESC keys to open the task manager. Select Mail in the list and click on the Force Quit button.
You should try to determine why Mail is having trouble quitting. This may be the sign of a corrupted mail database or other Mail file.

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