The iPhone cannot be synced. iTunes crashing.

There seems to be a whole “bunch of stuff” going on with my iMac 21” i3, and I just wanted to check in to see if anyone had experienced anything similar or had any advice.
First, when syncing my iPhone 4 last week I got this message:
"The iPhone cannot be synced. The disk could not be read from or written to."
iTunes at the same time was freezing up, so I forced quit (silly perhaps).
When I restarted iTunes I got this:
“iTunes Library does not appear to be a valid iTunes library file.  iTunes has created a new iTunes library and renamed the file to "iTunes Library(Damaged)"
Some research some frustration and some time got my iTunes back up and running.
I was still getting the "The iPhone cannot be synced. The disk could not be read from or written to." When attempting to sync by iPhone.
Finally I found a fix that worked online (not syncing photos!).
So that should be the end of the story.
But since then iTunes has been running SLLLLOOOOOWW, as has my system as a whole.
Then last night:
"The iPhone cannot be synced. The disk could not be read from or written to."
Followed by:
“iTunes Library does not appear to be a valid iTunes library file.  iTunes has created a new iTunes library and renamed the file to "iTunes Library(Damaged)"
So something be wack!
The only thing I could think of is I got an email from Apple telling me they needed to replace my hard drive free of charge as they were found to be faulty.
I’ve booked in with the Apple Store to have the drive replaced. But could it be the problem? Or do I have something else happening here.

Please post questions regarding unreleased software in the Developer's forum using your developer account credentials.
Stedman

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    Network Adapter Information
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