The itunes library file cannot be saved (-48)

After migrating my library from an xp machine to a new vista machine, I get this error whenever I open iTunes.
The itunes library file cannot be saved (-48)
The most annoying result appears to be that my video iPod does a full sync every time now (as it can't save the library file, this isn't surprising).
Anybody know how to fix this?

I am getting this error on my Vista computer. I've tried rebuilding the library and that didn't help. Interestingly I had the same error on my old XP computer. When I migrated my music from the old to the new I copied the music files but I created a new libary files; so that indicates to me that the problem is not Vista specific.
I am starting to wonder if it's a software confict, ie some software that I had installed on both computers or a corrupt file among my music.
There is another discussion about this error here, but there's nothing conclusive http://discussions.apple.com/thread.jspa?threadID=1202649
BTW I have found that the error always occurs when I connect my 2nd generation Shuffle, but it also occurs randomly, particularly shortly after I have opened iTunes (even if I have not made changes that would require writing to the library file).
Message was edited by: Madam

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