The Itunes Music Library file cannot be saved. An unknown error occurred

This is driving me crazy.. I've uninstalled Itunes, used msciuu2 to clean up the installer(s), deleted any ITUNES directory located on my computer. cleaned out all itunes entries in my registry .... start reloading my podcasts and I get the same error all over again..
I do not have Itunes as my default player and it uses its own directory d:\My Documents\Itunes vs d:\My Documents\My Music folder (as I do NOT want WMP or Itunes to conflict with the music libraries.

I wish I could say either the Reg changes or disabling McAfee anti-virus worked for me, but I am still stuck.
I am running 6 on a Win2K Server. My account is admin and I have confirmed it is not a permissions issue or a lock file issue.
I receive the -1450 error in the following conditions:
1. iTunes attempts to save library
2. iTunes attempts to download a purchase (actually, it appears to occur after the file is downloaded, but it does not save the file to disk, although it thinks it downloaded the file)
3. iTunes attempts to rip a CD. This is a random occurrence whereby the rip stops at some random place mid-song. I may have it happen immediately, then work for a few songs, then happen again. I have been able to rip 2-3 CDs before seeing the error, whereas other times it seems to occur with the first song and I retry a few dozen times before it works again. I have used 2 different CD drives.
4. iTunes attempts to sync with the iPod. In this case, I randomly receive the error that I need to reset my iPod to factory defaults. However, after a day of waiting, it works again. I actually tried to reset the iPod to factory defaults when I was first presented with this problem--it caused a write error and crashed the iPod to the point where it could not even be recovered by the Apple staff at the Apple store; they gave me a new replacement unit.
I have to think this is a programming issue on the iTunes side, specific to Win2K (and possibly NT). Has anyone had this problem on an XP box?
My next step is to move all my files and software over to my XP box and see if I receive the same errors. Should that fail, I'll use a non-iTunes product until a software update is released.
Anyone from Apple checking into the -1450 error issues?

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    library has disappeared- I get the following error
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    I have like 5,000 songs so I keep them on an external
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    maybe the warning means that the disk is write
    protected, so I right clicked on the drive (and
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    I wish I could say either the Reg changes or disabling McAfee anti-virus worked for me, but I am still stuck.
    I am running 6 on a Win2K Server. My account is admin and I have confirmed it is not a permissions issue or a lock file issue.
    I receive the -1450 error in the following conditions:
    1. iTunes attempts to save library
    2. iTunes attempts to download a purchase (actually, it appears to occur after the file is downloaded, but it does not save the file to disk, although it thinks it downloaded the file)
    3. iTunes attempts to rip a CD. This is a random occurrence whereby the rip stops at some random place mid-song. I may have it happen immediately, then work for a few songs, then happen again. I have been able to rip 2-3 CDs before seeing the error, whereas other times it seems to occur with the first song and I retry a few dozen times before it works again. I have used 2 different CD drives.
    4. iTunes attempts to sync with the iPod. In this case, I randomly receive the error that I need to reset my iPod to factory defaults. However, after a day of waiting, it works again. I actually tried to reset the iPod to factory defaults when I was first presented with this problem--it caused a write error and crashed the iPod to the point where it could not even be recovered by the Apple staff at the Apple store; they gave me a new replacement unit.
    I have to think this is a programming issue on the iTunes side, specific to Win2K (and possibly NT). Has anyone had this problem on an XP box?
    My next step is to move all my files and software over to my XP box and see if I receive the same errors. Should that fail, I'll use a non-iTunes product until a software update is released.
    Anyone from Apple checking into the -1450 error issues?

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