The new version of iTunes won´t run and i get an error message

that says the program has detected "a problem with your audio configuration".
How can i fix this without loosing songs etcetera?

I would try reinstalling iTunes to see if that will correct the issue. Follow this article and you will not loose your music.
http://docs.info.apple.com/article.html?artnum=93698
Let me know if it gives you the same error.

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