The temporary file path is not valid.  Lightroom cannot start

Windows XP, SP3, Lightroom 2.5.
External hard drive starts acting funny.  Round here we expect hard drive failure, so I order a new drive and when it arrives copy the backup onto the new drive.  The new drive has the same drive letter as the old one, but not the same name.  When I try to open a catalog I get: "The temporary file path is not valid.  Lightroom cannot start."  The catalogs seem to be fine, as when I open lightroom directly, not by clicking the .lrcat file, catalogs look normal.  If I copy the lrcat file to my internal hard drive it opens.  If I create a new catalog on the external drive I get the same problem.
I have tried deleting the preferences file.  I have tried deleteing and reinstalling lightroom.  I have used the external HD on another computer with lightroom and it opens normally.
All I can imagine is that there is some setting, somewhere in the registry which does not get erased when the lightroom gets re-installed.  Any guesses?
I am at a loss!  Please hope me!

Could be your Windows tempfile path is messed up. You could try going to Control Panel/Advanced and pushing the Environment Variables button.See what the TEMP and TMP variables are set to.
Under "User Variables", both of mine are set to C:\Documents and Settings\<my name>\Local Settings\Temp.
Under "System Variables", both are set to C:\Windows\Temp.
Make sure that the directories referred to are legal and on accessible drives. Make sure they aren't read-only. It wouldn't hurt to create them if they don't exist.
It's worth a try, I think.
Hal

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