Time Machine won't even launch: "Error code -43"

Thwarted from the outset, I can't even launch the app.
Any clues?

Hi All
I also cannot launch Time Machine (posted a separate thread here http://discussions.apple.com/thread.jspa?threadID=1244151&tstart=0 but no replies there yet)
I have a Journaled HFS+ external drive attached, I have turned TM on in the prefs and it has completed a number of backups. The 'backupdb' folder is visible on the backup drive.
However, I cannot get the application to launch, no matter what - click on the dock icon, click on the icon in apps, whatever. The dock icon does not even bounce. There is no response.
I want my over the top galactic animation too!
Anyone seen this happen or know why it might?

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