TMG Stops responding every 4 days / many connection drops with idle vpn connections

Hi everyone!
I am running a TMG Firewall with about 200 users connected on Server 2008 R2 - patch level 7.0.9193.601.
It is virtualized on a Hyper-V 2008 R2. Additionally we have 4 IPsec Site2Site VPNs configured in Windows Advanced Firewall - as TMG doesn't provide such a comfortable way to configure them directly in TMG.
About 3 Months ago that TMG started to lose connectivity from time to time. At first we were not monitoring that problem precisely as we thought it was an isp issue but some days before christmas that tmg server just dropepd every outgoing connection
and stopped listening!
I was able to control the server over hyper-v directly but no connection in or outbound could be established. (no VPN inc or surf outgoing)
I checked the event logs and there was NO other error than the errors from TMG connection verifiers...
As far as I was able to tell tmg still worked as far as logs and engine was conserned but no routing was done at all!
The last resort was to reboot the TMG then everything worked as before...
This behavior then appeard every 4 days... - simple workaround scheduled reboot every 3 days!
But that is no statisfying solution.... additionally some vpn users reported that their connections has quite annoying drops from time to time, unfortunately I was not able to trace the error.
Possible sources that I can exclude:
-Backup (online snapshot with ArcServe - the server was NOT saved)
-AV (Symantec Endpoint protection 12.1 - was uninstalled nothing changed)
Any ideas??
Best regards

Hi,
opening a MS case seems not to be so easy...
As long as I have no clue whats going on exactly there is no ms case.
Any other suggestions??
I started collecting Perfmon data: everything seems to be OK.
- hardly any backlogged packets
- during working hours about 10 pages / sec (memory)
Some Values:
Free System Page Table Entries: 33.555
Pool Nonpaged Bytes: 88.646.372 Bytes = 84,53 MB
Pool Paged Bytes: 266.842.112 Bytes = 254,48 MB
System Driver Total Bytes: 4.812.800 Bytes = 4,5MB
Handle Count (wspsrv): 11.338Private Bytes (wspsrv): 821.944.320 Bytes = 783,86 MB
Working Set (wspsrv): 609.697.792 Bytes = 581,4 MB
Virtual Bytes (wspsrv): 1.747.615.744 Bytes = 1,666 GBThread Count (wspsrv): 69
I'll keep collecting data for two days because my last reboot was 2 days ago - if my observations were correct TMG will stop responding monday morning or during lunchtime at latest.

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