Today, iTunes does not open

yesterday, iTunes was fine, this morning iTunes does not open.  Restarted, problem not resolved.  No new devices added nor deleted.  Ideas?

For general advice see Troubleshooting issues with iTunes for Windows updates.
The steps in the second box are a guide to removing everything related to iTunes and then rebuilding it which is often a good starting point unless the symptoms indicate a more specific approach. Review the other boxes and the list of support documents further down page in case one of them applies.
Your library should be unaffected by these steps but there is backup and recovery advice elsewhere in the user tip.
If you've already tried a complete uninstall and reinstall try opening iTunes in safe mode (hold down CTRL+SHIFT as you start iTunes) then going to Edit > Preferences > Storeand turning off Show iTunes in the Cloud purchases. You may find iTunes will now start normally.
tt2

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    Symptoms
    When isolating issues and/or troubleshooting software issues in OS X, you might want to use a different user account. Learn how to use this technique to narrow down the cause of an issue.
    Resolution
    The issue at hand may simply be caused by a bad preference setting or user-specific data file. With proper isolation, you can avoid time-consuming and inappropriate troubleshooting methods.
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