TS1717 When I try to open iTunes I get this message; The iTunes Library.itl cannot be found or created. The default location for this file is in the " iTunes" folder in the "My Music" folder.  I have uninstalled and re-installed EVERYTHING apple related.

iTunes used to open with no issues, then suddenly did this upon launch. So I found every file associated with apple and whiped the computer clean; reinstalled then tried to open iTunes, with fingers crossed............no luck. I am stumped and frustrated. Don't know what to do next. Can anyone help me?

Look in your Home > Music folder.  There should be an iTunes folder there and it should have a number of files and folders including one called library.itl  You want to guide iTunes to that file.  If you don't see that file or folder then in your next post you will have to be very specific as to what you do see or how you have your iTunes set up because that's where it should be according to default settings.

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