TS3540 my iphone wont connect to itunes because of invalid response please help

iTunes could not connect to my iPhone” because an invalid response was received from the device. i have tried updating my itunes and restarting my powerbook pro, i have even looked to remove the file "com.apple.usbmuxd.plist~orig" which wasn't there. I am losing the will to live!

The article you attached suggests you are running OS X 10.6.  Is this true?  If so, it is the cause of your issue.
The iPhone 5S, being a brand new machine, needs a new version of iTunes.  The current iTunes is 11.1.3.  That version requires at least OS X 10.6.8, and seems to do better with later versions.

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