TS3742 MacBook starts to boot and then has the "no" symbol, (circle with line through it).  Tried to reboot in safe mode and got the same thing.  Ideas?

MacBook starts to boot and then has the  "no" symbol (circle with a line through it)
Tried to reboot but now get the ?
Any ideas?

Something is messed up with the Disk.
"Try Disk Utility
1. Insert the Mac OS X Install disc, then restart the computer while holding the C key.
2. When your computer finishes starting up from the disc, choose Disk Utility from the Installer menu at the top of the screen. (In Mac OS X 10.4 or later, you must select your language first.)
Important: Do not click Continue in the first screen of the Installer. If you do, you must restart from the disc again to access Disk Utility.
3. Click the First Aid tab.
4. Select your Mac OS X volume.
5. Click Repair. Disk Utility checks and repairs the disk."
http://docs.info.apple.com/article.html?artnum=106214

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