Two i-tunes loaded on one computer

Question

Can I set up two accounts on one computer so when either my wifes i-pod or mine are attached it goes to the right song playlist for syncing?

Answer 1

You'll not get either of theses two "account" methods to automatically, you'll need to be logged onto the correct one. However, it's possible to have multiple libraries in a single Windows User account. To create or access a second (or more) library, hold down the Shift key in Windows when launching iTunes. In the resulting dialogue you will get the option to create a new library or navigate to the other Library.
Note: You can only have one Library open at a time and iTunes will default to the last library opened if you don't use the keyboard command to choose one. This can prove tricky when using multiple iPods, if you don't use the keyboard command you can risk syncing to the wrong library: Using multiple iTunes libraries -Windows
Another option is to create a separate User account for each person on your PC. Different accounts by definition would give you completely separate libraries. Each account has it's own iTunes folder, Library and iTunes Music folder and you load it with CDs etc just as you did with your original one. The iPod can be set to update however the owner chooses, sync all, manual or sync specific playlists
I don't use Windows so I can't give you a step by step on that one, however I can point you to another web page which should help you out. You can read about Windows user accounts here:
Create and customize user accounts in Windows XP
Create A New User Account In Vista
If you wanted to share a single library then you could automatically update the iPods without having to choose a library or account first. If you want to share the one library, you can set the iPods so that they only get updated with only certain playlists (you can update from more than one if you wish):
iPod - Syncing Music
Syncing Music to iPod shuffle
Choosing the update option "Sync Music - Selected playlists" allows you to create a playlist specifically for the iPod and drag the tracks you want into it. If you tire of the list and want to change it, you just add or remove the songs you don't want. The ones you take out out remain in the library to be used some other time if you choose.