Type changing in PDF

Hello all,
I have created a page in InDesign CS4, using open type fonts, saved it out with an Adobe PDF preset as HiRes PDF. Title on page is all caps. When I go to Adobe Acrobat Pro v9.4.3, under Discussion/Reduce File Size . . ., do a save as for a lores doc, the caps are now cap/lc and the spacing between letters has changed. Has anyone else run into this issue? Appreciate any info.
Thanks

A screenshot won't show much, if you sent the file to yourself using yousendit.com and posted the link here that would help.
You say "save out", do yo umean Export?  As in File > Adobe PDF Presets > Press Quality or one of the other presets?  There isn't one called Hi-Res which makes me think you might be producing it some other way?

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