Unable to click on some of the tools - cannot select them.

I am using Indesign CS3 and am unable to click on the selection tool or direct selection tool. Also when I have a text selected and go to edit, I can not click on the font or any other attribute to change. I am able to use the shortcut key A and V to select them, but can not physically select them. This is very frustrating. I have uninstalled and reinstalled, I've used the cleanscript, I've deleted the preferences, I have gotten a brand new installation cd (thinking it was the original cd) and tonight I finally broke down and wiped my harddrive and reinstalled the operating system...still doesn't work. Please help!
I'm running a Dell Studio 1737, Windows Vista, 32bit, 4GB Ram, Intel Core Duo CPU T6400 @ 2.00GHz, ATI Mobility Radeon HD 3650 graphics card.

Wow, thanks. I had this issue also and I never would have fathomed that a desktop theme setting would cause this problem. How unrelated of a solution can you get?
Incidentally, I am running Windows7 Ultimate with Abode Master Collection CS4. It took a bit to figure out where the AERO settings were, but I found it;
Open the Control Panel and go to Personalization and select Window Color (icon at the bottom)
or by right-clicking the desktop and selecting Personalize and select Window Color
or navigate to here : Control Panel\Appearance and Personalization\Personalization\Window Color
Then uncheck (disable) Enable Transparency
Optionally, save this as a new Theme, so you can easily find it again.
Hope this helps anyone else running Win7

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Unable to click on some of the tools - cannot select them.

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