Unable to launch Adobe Reader using ShellExecute with Protected Mode on

HI
Using the latest Adobe Reader 11.0.9, I open a PDF via ShellExecute in a legacy 32bit application, I get an unsupported configuration dialog and prompt to open with Protected Mode disabled always, once or don't open.
I need it to open with Protected Mode enabled.
The folder is in the Security (Enhanced) Privileged Locations.
I turned Protected Mode logging on and I see these messages when I call ShellExecute:
[12:02/18:17:12] interceptions setup failed - error:0x0
[12:02/18:17:12] Failed to add target - error:0x0
[12:02/18:17:12] Failed to launch sandbox process. ResultCode: 1 error:0x5A4
[12:02/18:17:12] Sandbox Process Initialization Failed - error:0x5A4
I've read the Unsupported Configurations section of the Protected Mode Troubleshooting guide but nothing matches my system as far as I can tell.
I am running the 32bit legacy application in Windows Server 2008 R2 (64bit) as a member of Domain Administrators
What can you suggest is the unsupported configuration?
Thanks
Craig

I've tried another PDF viewer and it works fine so I think it's time to say goodbye to Adobe Reader.

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