Unable to Open Attachments

I have just downloaded Adobe Reader 10.1 upgrading from earlier version, but now I am having problem
opening some attachments.  Get error message:  "This application has requested the Runtime to terminate
it in an unusual way.  Please contact the application's support team for more information."  Any suggestions
on how to get this resolved?  Download 10.1 again?

Can you open Adobe Reader by itself?
Can you try to upgrade to the latest version 10.1.3?
Can you try to turn Protected Mode off?  (Edit | Preferences | General; uncheck Enable Protected Mode at startup.)

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