Unable to open mail box which I set up in mac

I bought my mac book pro recently in the month of Nov 2013. Past from few days i was unable to open my mail box and to knowledge i haven't done any updates either. In additon to that it's not allowing my Mac to shutdown or restart. The messgae i'm getting is "Quit Mial or Try Again"
Can someone please help me?

Hello there, Vijaynedu.
The following Knowledge Base article offers up how to Force Quit an application that may not be shutting down or inhibiting other actions on your Mac:
OS X: How to quit an unresponsive application using Force Quit
http://support.apple.com/kb/ht3411
Thanks for reaching out to Apple Support Communities.
Cheers,
Pedro.

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