Unable to read PDF files

I have a new Mac Mini which I just migrated from an old iMac (the one with the half-dome base). Some PDF files came over with it and some have been received since. When I click on them I get the following message:
You can't open the application because it is not supported on this architecture.
Any thoughts?

I'm supposing that your old iMac was a PPC model that was able to run the "Classic Environment" -- and that you migrated over an old version of Adobe Acrobat or Reader that required the Classic Environment, which is not available on your new Intel Mini. Locate that old Adobe Acrobat or Reader and eliminate it on your Mini.

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