Unknown error (-50), ipod won't save sync options

OK, I'm having one **** of a problem. The error message reads (-50) "an unkown error has occoured" apple support has been on no help so far...
Basically every time I try to save new settings in itunes and hit apply this message comes up, and then another "ipod cannot be updated disk cannot be read or written to" itunes freezes up then an "unkonwn error has occoured (-50)" error message a minute later.
Then when I reconnect it it says that no folders to download has been saved. I've tried to "enable disk usage" but that dosen't save.
This problem was temporaily eleviated when I downloaded 1.0.2 but then when I had to reset my ipod because it froze up, it wouldn't function agian. Just when I thought I had the problem solved. The same ** frustrating cycle.
I thought maybe downloading 1.0.2 agian would help but it reads that is already downloaded.
I'm stumped guys, please help.

http://discussions.apple.com/thread.jspa?threadID=640556&tstart=0
Check the second half of the post. deals with error 50.

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