Unknown file has appeared on desktop and wont delete

After checking emails and surfing the web for a while I went back to my desktop and found an unknown excel file on there called 38DB0D00 which wouldn't let me open it or delete it with cmd+backspace.
Is it malicious? How do I get rid of it?

What does the Finder displays when you try to open or delete ? right click on the file and choose Get Info and check the Sharing & Permissions section to notice who is the owner and what are the permissions and notice if the Locked option is ticked .

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I have pictures in IPhoto that I want to maintain the security and restrict access. The photos are confidential. The problem is that the files show up in screen saver and desktop. In OSX.5 how do you remove iPhoto files from desk top and screen saver? or prevent desktop or screen saver from accessing the files?

Walter:
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An unknown excel file has appeared on my desktop. It cannot be deleted and I cannot get any information about it. Is this malware? How can I get rid of it?

An unknown excel file has appeared on my desktop. It cannot be deleted and I cannot get any information about it.
Is this malware? How can I get rid of it?

Hello Jeff,
Thanks very much for your reply. I looked over the article you mentioned, but I have tried all of these methods, but only get the response "The item “29394D00” can’t be moved to the Trash because it can’t be deleted." Similarly, I cannot Get Info on the file. This is why I'm so concerned, it just appeared on my desktop, but I cannot touch it, or open it or delete it...
If you have any more tricks up your sleeve, I'd love to hear about them...
Derek

My ipod touch 1st gen has gone into recovery and wont restore because of a error 1 or something like that can someone help me quick this ipod is my little cousins and i dont want her mum to find out what happend

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http://blogs.technet.com/b/the_microsoft_excel_support_team_blog/archive/2013/09/07/quot-cannot-open-the-file-because-the-file-format-or-extension-is-invalid-quot-opening-office-files.aspx
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Unknown file has appeared on desktop and wont delete

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