USB comm to a 9 Pin device

I have a device that we sell and a LV application (built using V5.1) that is a 9pin serial and receives simple ascii commands and ships back ascii data. With the demise of the 9 pin, many of our users have gone to a USB to 9 Pin adapter and all works ok. Lately, we have been getting intermittent results on newer operating systems. Basically, sometimes the communications occurs and sometimes it does not, even on the same PC/device. I am looking for suggestions of what might be going on and possible solutions. Thanks is advance for any help.

The NI USB-232 boxes support both DTE and DCE operation modes in addition to an "Auto232" mode that simplifies cabling (null-modem? straight-through? doesn't matter!). Also the USB-232 has indicators for transmit, receive, error, and signal validity which aides device communication development. In addition NI's serial products support 5,6,7,8 data bits, NOEMS parity, and RS-232 baud rates up to 230.4k with a driver architecture designed from the ground-up to support the higher serial bandwidth.
These features are all in addition to the world class support that differentiates National Instruments from other vendors.

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