USB hubs quit working with 10.7.2

I have a Mac Pro, dual quad-core 2.8GHz Xeon, 10GB ram. Three D-link DUB-H7 usb hubs. After the update to 10.7.2 and iTunes 5.0.1 (not sure exaclty when), my usb devices & hubs quit working properly. For a while they would work occasionally.
I have a USB keyboard which works if it's plugged in directly when the computer boots. But other devices (external drives, flash card reader, iPod dock, USB display) don't work at all. I tested the hubs with another Lion system, and they work on that. iTunes wireless sync quit as well.
I've tried resetting PRAM and SMC. Neither fixed the problem. Tried repairing permissions. No change. Rebooting (many times).
Could it be a USB driver conflict? I removed VirtualBox usb drivers, as well as Parallels, but not vmware, which I also own.
When I plug in a device, I get 'trouble enumerating' and then "The IOUSBFamily was not able to enumerate a device." in the system.log
Any ideas? Is my motherboard dying? If so, why does the keyboard still work, and nothing else?

Followup info. I reset the PRAM and booted into 10.5.1, on another drive.
This time, similar behavior; HID devices (keyboard, mouse, bluetooth) work fine. Hubs (which work fine on another Lion computer!) generate a bunch of console errors:
11/19/11 11:21:31 AM kernel USBF: 746.706 USB Device IOUSBHubDevice is violating Section 9.3.5 of the USB Specification -- Error in GetConfigDescriptor( wLength = 4)
11/19/11 11:21:31 AM kernel USBF: 746.707 AppleUSBHub[0xf536000]::ConfigureHub No config descriptor
11/19/11 11:21:31 AM kernel USBF: 746.707 AppleUSBHub[0xf536000]::start Aborting startup: error 0xe0004056
11/19/11 11:21:31 AM kernel USBF: 746.707 IOUSBHubPolicyMaker[0xf536000]::start - ConfigureHubDriver returned false

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