USB mouse trouble and dissappearing program

I just bought a new MacBook and started using it Monday. When I close the lid it goes into sleep mode. Whe I open the lid back up it wakes up all things normal. However, the mouse won't function. I have to unplug and plug it back in and it's working again. The computer will go to sleep in its own within 5-10 minutes (I assume it's preset to this). When I wake it back up the mouse won't function again and this time the red optical light starts blinking rapidly.
Another thing I noticed... I have the gmail notifier installed. The Gmail icon was displayed right next to the bluetooth icon. Today I opened the lid and the gmail icon was nowhere in sight. I waited for a while still did not appear. It was like the program just dissappeared. I had to download and re-install the Gmail notifier.
What do these things mean? I have had duds in the past. This is my 3rd laptop in 3 years. I'm trusting this one will not give me problems cause I like apple's products!

Here's the page for the mouse on amazon.com
http://www.amazon.com/Targus-PAUM01U-Ultra-Retractable-Optical/dp/B00007LTAQ
Several Mac users reported using it with no problems, and it did not require installing any software.
There have been some USB issues reported on these boards with OSX 10.4.10 -- so perhaps that is the problem.
It might be worth playing with the mouse/trackpad settings that control whether or not the trackpad is active when a mouse is attached.

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    Message was edited by: Nitnellav
    Message was edited by: Nitnellav
    Message was edited by: Nitnellav

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