Using a different computer to the one for set-up

With iPhone coming to Orange, I think I'm now going to get one.
I have a MacBook, but the motherboard failed and it is currently in for repair. It wouldn't be back by the time I get the iPhone. I also have a Dell PC with iTunes.
When my Mac comes back, I will be using it as my primary computer and would manage my iPhone through it. I actually want to get rid of the PC eventually. If I activate the iPhone on the PC when I first get it, will this cause me problems when I want to switch to using my Mac?

Welcome to the discussions,
You won't have problems if you transfer your purchases and back up your phone manually on the mac before you start to sync with it. Transferring your purchases will copy your bought items from the itunes store to your mac, after your media data got erased from the phone, you can restore it from the manual backup you did. Make sure to have autosync disabled in itunes. About backups: http://support.apple.com/kb/HT1766 and back up and restoring: http://support.apple.com/kb/HT1414
Don't forget to set up at least one contact and event on your mac to be able to merge calendars and contacts when you sync for the first time.

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