Weird Photoshop launching Problem with Leopard - Help!

Program: Photoshop 10.0 from CS3 Design Premium
Computer: Mac OSX leopard Version 10.5.1., Intel core 2 Duo.
Problem: When I launch Photoshop I get this message: "Could not initialize Photoshop because the file is locked. Use the 'Get Info' command in the Finder to unlock the file.
Well, I select the program icon (which is what the message is referring to as "the file") then I go to the 'Get Info' window it shows that program is not locked. I have uninstalled the program, and even the whole suite and reinstalled it a number of times, but nothing works. HELP!
All the other programs open fine except for the InDesign which will open, but not for long before it quits. No error message pops up with the InDesign.
HELP!!!
LK

Hi Folks!
Well, I have spent a lot of time going back and forth between Adobe and Apple techs for days, and it comes down to this:
I was told by both that I could do a clean install of the Leopard and chance that the Adobe Photoshop and InDesign will still have the same problems, or I can wait for Adobe to work on fixes for the software.
When I originally installed the Leopard it was installed over the original Tiger operating system. I have loads of software on the computer, Quark, MS Office, CS3 Design Premium, and much more and other than some issues with my AOL everything works perfectly except the problem mentioned above with Photoshop and InDesign. AOL is working on a new software for Leopard which should come out soon. It seems that Adobe needs to do the same with Photoshop and InDesign, or make fixes for the many problem, which from I read they are trying to do.
I would really hate to do a clean install on my computer, with all the work that comes with it reinstalling software, printer drivers, etc., just to find that Photoshop and InDesign will still have problems.
From some of what I read from others on this string, and in other areas of the forum, it looks like people are often having problems with Photoshop and InDesign even if they did a clean install.
If anyone had done a clean install and are still having problems, please mention it on this string.
THANK YOU!!
LK

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