Weirdness; No bash, no sudo, no locks to click, but lotsa smbd

I'm having a problem which is rendering my machine pretty unusable. After I first login in, everything is hunky dory. But after a few minutes programs just start getting unresponsive left right and centre. Symptoms also include that my terminal shell goes wonky. Starting a terminal window just shows the last login message and the blinking cursor, but no prompt. Typing commands in doesn't do anything.
If I run bash I get a prompt, but I can't use sudo.
If I need to authenticate anything, the lock from the "click on the lock to make changes" doesn't appear. I'm guessing this is related to my sudo problem.
Alo when I check the processes with top I find that there are something like 50 instances of the smbd daemon running. I added deadtime = 5 to the /etc/smbd.conf file, and it has culled the numbers somewhat. But I think this is a symptom, not the cause - those daemons aren't consuming any cpu or memory resources to speak of.
I think it might have something to do with recently installing Adobe CS4. It seemed to have started at the same time. Mind you I did have to throw away a lot of stuff to make room for it. Could I have inadvertantly thrown away some essential bit of system kit?

Hi st!b,
Where did you throw stuff away from?
Have you done any Disk/OS maintenace lately?
One way to test is to Safe Boot from the HD, (holding Shift key down at bootup), run Disk Utility in Applications>Utilities, then highlight your drive, click on Repair Permissions, Test for action in Safe Mode...
PS. Safe boot may stay on the gray radian for a long time, let it go, it's trying to repair the Hard Drive.
Reboot, test again.

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