What are ipad .panic.plist

My iPad2 keeps crashing, I see many .panic.plist events in diagnostics and usage which shows panic(cpu 0 caller 0x807db6df): "i2c2::_interruptFilter interrupt when no transaction in flight;last read status.
Does anyone know what this means? I have preaviously done a factory reset and full restore but the crashes keep happening.  Some days no crashes then the next day maybe 5 in an hour.  Before upgrading to iOS5 I loved my iPad no problems and no resets but since upgrade things have been getting worse.
Please help if you can. Regards.

Since you already did a Reset and a Restore, assume you have a hardware issue (they often result in panic.plist reports) and take it to a Genius at your local Apple Store for diagnostics.

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