What causes the itunes.msi error and what is the best way to fix it?

i have windows xp. when trying to update to itunes 8.2-the installer can not locate the Itunes.msi file. i found the file but the installer can't use it. this is also the case when i try to delete itunes and/or reinstall.
what causes this error and could someone point me in the right direction as how to fix this.
also i can't open itunes without having my ipod connected..so annoying. is that normal?
thanks. =)

Apple will exchange your iPod for a refurbished one for $199 for 64 GB 4G and $99 for the other 4Gs. They do not fix yours.
Apple - iPod Repair price                       
A third-party place like the following maybe less. Google for more.
iPhone Repair, Service & Parts: iPod Touch, iPad, MacBook Pro Screens
Replace the screen yourself if you are up to it
iPod Touch Repair – iFixit

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