What should I do if whenever I open Itunes it freezes my whole computer and the mouse doesn't move?

How can I prevent my mac book pro from freezing whenever I open Itunes. (Whenever I open Itunes my whole computer freezes and I can't move or do anything) What should I do??

iTunes
http://www.apple.com/support/itunes
you might need help with OS X more than iTunes though.

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