What will happen to my previously installed software after upgrading mac to OS X Yosemite?

I'm new to mac OS and I want to upgrade my mac from OS X Mavericks to Yosemite. I want to know if that upgrade would affect my previously installed software (e.g Wolfram Mathematica).
Do I have to re-install those software after upgrading to Yosemite?

When the installer is downloaded from the App Store, it is a good idea to make a copy of it with a different name and in another location from the Applications folder, as the original disappears after running.
The installation will leave the user account intact, with your apps and files. However, not all apps will be updated for Yosemite and to save future problems it is advisable to go to the developers' websites and get the latest version, before you make the move.
I see from Roaring Apps, that Wolfram Mathematica may not yet be ready for Yosemite.
http://roaringapps.com/app/mathematica-home-edition

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