When I bootup first thing in the morning it won't have sound and boots in safe mode then if you reboot it works ok can anyone help

The system has been restored and still does it

Hmmm, bit of a hail Mary here, but...
Open Audio Midi Setup in Applications>Utilities, see the input & output options & KHz setting there, some things will change it for their own use, then not set it back. Or if toggling things brings it back.
To find out if it's system wide or user specific, try this...
Open System Preferences>Accounts, unlock the lock, click on the little plus icon, make a new admin account, log out & into the new account.
Does Sound work in the new account?

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