When I click on Safari I get C:\Windows\system32\WindowsCodecs.dll is either not designed to run on Windows or it contains an error"

I also get the same error message when I try to open Quicktime.

I suggest that you reinstall the Microsoft Visual Studio 2010 redistributable https://www.microsoft.com/en-us/download/details.aspx?id=5555
If you are on a 64-bit system you should also install the x64 version http://www.microsoft.com/en-us/download/details.aspx?id=13523

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