? When I try to use Adobe reader or open a PDF file

I get the Error "Invalid plugin detected Adobe will quit" How do I fix this?

In that case, you might try this forum: http://forums.adobe.com/community/acrobat/acrobat_windows This one covers a different Adobe product.
What it sounds like is that one of the helper programs that reader uses, called plug-ins, isn't working. If you've recently added a plug-in, you might try removing it. Otherwise, I would be inclined to uninstall reader and reinstall the latest version.

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