When I turn iTunes on "an unknown error occurred (-42110) pops up?

When I turn iTunes on "an unknown error occurred (-42110) pops up?
It started happening after downloading the latest version of iTunes.
As well, I'm not sure if it has something to do with it but when I download purchases and they show complete, the next time I turn iTunes on, the purchase starts downloading again which is holding up other downloads.  Frustrating.
Thanks!

Try this user tip for the 42110 error
https://discussions.apple.com/docs/DOC-4831

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